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Occupational causes of lung cancer.
Steenland K; Loomis D; Shy C; Simonsen N
Occupational and environmental respiratory disease. Harber P, Schenker MB, Balmes JR, eds. St. Louis, MO: Mosby, 1995 Jul; :589-607
Occupational causes of lung cancer were considered with emphasis on human epidemiology. Agents determined to be definite or probable lung carcinogens as classified by the International Agency for Research on Cancer were considered, including: silica (14808607), asbestos (1332214), products of the combustion of fossil hydrocarbons (soot, diesel engine exhausts, coke oven emissions, and coal gas and coal tar volatiles), radon progeny (10043922), arsenic (7440382), acrylonitrile (107131), nickel (7440020), bis- chloromethyl-ether (107302), chromium (7440473), beryllium (7440417), and cadmium (7440439). Major findings and outstanding issues for each agent were discussed. The role of smoking was also considered; observed interactions between smoking and carcinogenic agents tended to be somewhere between additive and multiplicative in nature. The authors estimate that approximately 9% of male lung cancers and 2% of female lung cancers in the United States are attributable to exposure to occupational lung carcinogens; estimates vary depending on selected data and assumptions.
Lung-cancer; Respirable-dust; Health-hazards; Occupational-respiratory-disease; Lung-irritants; Occupational-exposure; Respiratory-system-disorders; Exhaust-gases; Coal-mining; Metal-compounds; Cigarette-smoking; Industrial-exposures
14808-60-7; 1332-21-4; 10043-92-2; 7440-38-2; 107-13-1; 7440-02-0; 107-30-2; 7440-47-3; 7440-41-7; 7440-43-9
Harber P; Schenker MB; Balmes JR
Occupational and environmental respiratory disease
Page last reviewed: July 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division