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Radon-exposed underground miners and inverse dose-rate (protraction enhancement) effects.
Lubin JH; Boice JD Jr.; Edling C; Hornung RW; Howe G; Kunz E; Kusiak RA; Morrison HI; Radford EP; Samet JM; Tirmarche M; Woodward A; Yao SX
Health Phys 1995 Oct; 69(4):494-500
The data from 11 studies of underground radon (10043922) exposed miners, which included 2,701 lung cancer deaths and 1.2 million person years of observation, were analyzed with respect to the existence of the inverse dose rate (protraction enhancement) effect and the diminution of the effect at low total dose. Data from the studies provided evidence of a protraction enhancement effect for high linear energy transfer (LET) radiation. It was stated that for high LET radiation at low total dose, there is a low probability of more than one alpha particle traversing a cell, and therefore, the inverse dose rate should decrease. The results of the data analyses supported this assertion for exposures under 50 Working Level Months. The authors conclude that in using miner based models for estimating radon effects in homes, where durations of exposure are longer and radon progeny concentrations lower despite the lower cumulative exposures, the inverse dose rate effect and its diminution at low rates should be considered.
NIOSH-Author; Underground-miners; Radon-daughters; Workplace-studies; Statistical-analysis; Risk-analysis; Pulmonary-cancer; Epidemiology; Radiation-exposure; Author Keywords: radon; cancer; lungs, human; epidemiology
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Page last reviewed: December 18, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division