Respiratory cancer and other chronic disease mortality among silicotics in California.
Goldsmith-DF; Beaumont-JJ; Morrin-LA; Schenker-MB
Am J Ind Med 1995 Oct; 28(4):459-467
An epidemiological study was conducted on mortality risks associated with silicosis. Mortality rates were calculated for 590 cases of silicosis identified from a registry of Workers' Compensation Appeals Board Claimants for the period 1945 to 1975. State vital records were used to determine mortality risks to 1991. The well recognized association between silicosis and increased mortality due to tuberculosis and other nonmalignant respiratory diseases was confirmed in this analysis. The standardized mortality ratio (SMR) for tuberculosis was 56.34; the SMR for nonmalignant respiratory disease was 3.80. A significantly increased risk for all causes of death was seen among the cohort, along with increased SMRs cirrhosis of the liver, and for cancers of the trachea, bronchus, and lung. The SMR for cancer of the large intestine was 2.08. Significantly decreased SMRs were seen for cardiovascular diseases, as well as cancers of the prostate and lymphatic system. The authors conclude that patients with silicosis should be educated about these associated disease risks.
NIOSH-Publication; NIOSH-Cooperative-Agreement; NIOSH-Grant; Pulmonary-system-disorders; Silica-dusts; Occupational-exposure; Lung-disease; Mortality-rates; Cancer-rates; Gastrointestinal-system-disorders
Internal Medicine University of California Internal Medicine Davis, CA 95616
American Journal of Industrial Medicine
University of California Davis, Davis, California