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NIOSH Testimony on Risk Estimates from the Cadmium Cohort Study by L. Stayner, February 7, 1992.
NIOSH 1992 Feb:8 pages
This testimony includes a table summarizing the risk estimates from fitting the multistage model to a specific cadmium (7440439) cohort study. The risk estimates from fitting the multistage model to the cadmium study were intermediate between estimates derived from fitting the Cox and Poisson regression models. NIOSH further notes that the risk estimates from the Cox and Poisson models are about 50% higher than the estimates in the risk assessment report submitted earlier by NIOSH. The lifetime risk was calculated over the entire life span rather than the median life span. Lung cancer rates were used rather than respiratory cancer rates. NIOSH assumed a five stage model for the analysis, as this is the number of stages generally observed in other multistage analyses of lung cancer. The model was fit by varying the stage affected by cadmium exposure and the model fit best when NIOSH assumed that cadmium affected the third stage.
NIOSH-Author; NIOSH-Testimony; Stayner-L; Risk-analysis; Epidemiology; Cancer-rates; Mortality-data; Occupational-exposure;
NTIS Accession No.
NIOSH, 8 pages, 4 references
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division