Mortality in a cohort of antimony smelter workers.
Schnorr-TM; Steenland-K; Thun-MJ; Rinsky-RA
Am J Ind Med 1995 May; 27(5):759-770
A study was conducted on mortality in a group of antimony (7440360) exposed workers. Mortality was assessed in a cohort consisting of 923 Hispanic antimony smelter workers. Compared with rates for United States white males, deaths within the cohort from all causes were lower than expected as was overall cancer mortality and mortality due to lung and colon cancer, cardiovascular disease, and heart disease. Significant elevations in mortality rates were seen for cancers of the liver, biliary tract, and gallbladder in the workers compared with expected rates. When compared with ethnic specific referents, the mortality from lung cancer within the cohort was increased as was mortality from ischemic heart disease. A suggestion of increased mortality from nonmalignant respiratory disease was seen in the cohort as well. The authors conclude that increased mortality from lung cancer and nonmalignant respiratory disease may be associated with exposure to antimony. Possible confounders and limitations relating to the identification of appropriate reference groups were discussed.
NIOSH-Author; Antimony-compounds; Lung-cancer; Cancer-rates; Epidemiology; Mortality-studies; Epidemiology; Cardiovascular-system-disorders; Respiratory-system-disorders; Racial-factors
American Journal of Industrial Medicine