Cotton dust exposure, across-shift drop in FEV1, and five-year change in lung function.
Christiani-DC; Ye-T; Wegman-DH; Eisen-EA; Dai-L; Lu-L
Am J Respir Crit Care Med 1994 Nov; 150(5):1250-1255
A follow up study was conducted to examine respiratory symptoms, across shift change in forced expiratory volume in 1 second (FEV1), and pulmonary function in a large, stable group of cotton textile workers prospectively over 5 years. The study included 384 cotton workers and 403 silk workers, both active and retiring workers, in Shanghai, China from 1981 to 1986. A standardized respiratory symptom questionnaire regarding smoking history, byssinosis symptoms, and complete work history was administered. Pulmonary function was tested. Area samples were taken using vertical elutriators in the various work areas. Cotton dust and gram negative bacterial endotoxins were measured. The presence of byssinosis among cotton workers was 9.7% at the initial survey among those lost to follow up. The presence of byssinosis among tested cotton workers at the time of first survey was 7.3%. Referent subjects exhibited no byssinosis. Compared to a similar group of silk workers, the study indicated that cotton textiles workers suffered an accelerated loss of lung function over 5 years. The annual unadjusted change in FEV1 for all cotton workers was calculated to be 39.5 milliliters/year versus 30.6 milliliters/year for silk workers. The authors conclude that cotton exposure may have a substantial impact on the lung function of these workers, placing them at considerable lifetime risk of developing chronic obstructive pulmonary disease.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Lung-function; Pulmonary-function-tests; Lung-irritants; Cotton-industry; Textiles-industry; Cotton-dust; Plant-dusts; Airborne-dusts
Environmental Sci & Physiology Harvard School of Public Hlth 665 Huntington Ave Boston, MA 02115
American Journal of Respiratory and Critical Care Medicine