Childhood cancers associated with parental occupational exposures.
Occup Med: State of the Art Rev 1994 Jul; 9(3):495-539
The relationship between parental occupational exposures and childhood cancer risks was reviewed. Issues related to epidemiological methodology were described. Statistically significant relationships between brain, nervous system, and urinary tract tumors in children and paternal occupational hydrocarbon exposure, brain and nervous system tumors and work in welding or the metal industry, and leukemias and lymphomas and parental exposures to textile work or wood, paper, and pulp industry work have been reported. Other studies have suggested a relationship between paternal preconception exposure to ionizing radiation or electromagnetic fields and increased risks of childhood cancer. The authors conclude that some childhood cancers may be related to parental occupational exposures to chemical and/or physical agents but that there is a need for improved assessment methods. Questions about pathogenetic mechanisms and relevant timing of parental exposures need to be addressed.
Epidemiology; Occupational-hazards; Reproductive-hazards; Metal-compounds; Organic-solvents; Ionizing-radiation; Radiation-exposure; Occupational-exposure; Electromagnetic-fields; Cancer-rates
Gold-EB; Lasler-BL; Schenker-MB
Occupational Medicine: State of the Art Reviews. Reproductive Hazards
University of California - Davis