Vibrotactile and thermal thresholds in 4,456 male Vietnam era veterans were investigated using data collected by the Centers for Disease Control as part of the Vietnam Experience Study. Quantitative sensory measurements performed included vibrotactile thresholds and thermal thresholds from the index finger and large toe. The effects of skin temperature, height, body mass index, age, race, place of military service, smoking status, alcohol consumption, income, and testing examiner on sensory thresholds were estimated. General linear models were fitted separately for the two vibrotactile threshold and two thermal threshold outcomes. Results showed that the major covariates of finger and toe vibrotactile thresholds were age, height, body mass index, and testing examiner. The major covariates of the index finger thermal threshold were age, income, examiner, race, and smoking status, while those of the toe thermal threshold were height, income, and examiner. Alcohol consumption had almost no effect on thermal thresholds and only a small effect on vibrotactile thresholds. The authors conclude that the results provide a basis for selecting variables to control in epidemiological studies using vibrotactile and thermal threshold measurements.