NIOSHTIC-2 Publications Search

Effects of 27 MHz Radiation on Somatic and Germ Cells.

Cleary-SF; Liu-M; Cao-G; Merchant-R; East-J; Diegelmann-R; Collins-J

Department of Physiology and Biophysics, Medical College of Virginia Virginia Commonwealth University, Richmond, Virginia 1993 Dec:14 pages

00219219

In an effort to further understanding of the effects of radiofrequency (RF) radiation on somatic cell mitotic activity and germ cell function, cell suspensions were exposed to 27 megahertz (MHz) or 2,450MHz radiation under isothermal conditions in-vitro. Cell types included resting human peripheral lymphocytes, LN71 or RT2 glioma cells, Chinese-hamster-ovary cells, HeLa cells, and mouse spermatozoa. Studies were also conducted on liposome permeability, and a mathematical model was used to calculate radiation energy absorption in mammalian cell models. Evidence was found that direct dose or dose rate dependent alterations occur at a highly physiologically significant cellular endpoint. The in-vitro studies suggested that qualitatively similar effects may be induced by in- vivo exposure to electromagnetic fields at these frequencies. Physiologically significant cellular changes were the result of 27 and 2,450MHz continuous wave and pulse modulated radiation exposures under these conditions without heating. The discovery that radiofrequency radiation with no heating may significantly affect the worker requires consideration in assessing potential health effects.

NIOSH-Grant; Grants-other; Radiation-exposure; Mammalian-cells; Cell-damage; Electromagnetic-radiation; Nonionizing-radiation; In-vitro-studies; Reproductive-hazards;

Physiology and Biophysics Medical College of Virginia Box 694, Mcv Station Richmond, VA 23298

19931210

Final Grant Report;

913524.00

Grant;

1994

PB94-174497

A03

Grant-Number-R01-OH-02148

OEP

Other Occupational Concerns; Grants-other;

Department of Physiology and Biophysics, Medical College of Virginia Virginia Commonwealth University, Richmond, Virginia

VA;

Virginia Commonwealth University, Richmond, Virginia