Determination of arsenic(III) and selenium(IV) using an on-line anodic stripping voltammetry flow cell with detection by inductively coupled plasma atomic emission spectrometry and inductively coupled plasma mass spectrometry.
Pretty-JR; Blubaugh-EA; Caruso-JA
Anal Chem 1993 Dec; 65(23):3396-3403
Methods were developed for the determination of arsenic (7440382) and selenium (7782492) in urine using an on line anodic stripping voltammetry (ASV) flow system, interfaced with inductively coupled plasma atomic emission spectrometry (ICP-AES) and inductively coupled plasma mass spectrometry (ICPMS) detectors. With this method polyatomic interferences which arise from chloride in sample matrices are eliminated. Arsenic signals in ICP-AES were enhanced by as much as ten times through preconcentration of sample volumes. Using ICP-AES detection, recoveries for analyte spikes in 1:10 diluted urine were 102% for arsenic(III) and 91% for selenium(IV). With ICPMS detection, determination of certified selenium(IV) and selenium(IV) spikes in diluted NIST SRM 2670 elevated urine gave recoveries of 92 to 103%. Recoveries of arsenic(III) spikes in diluted urine ranged from 94 to 113%. High levels of chloride matrix exhibited little effect on the arsenic signal with ICP-AES or ICPMS detection.
NIOSH-Author; Analytical-methods; Analytical-chemistry; Chemical-analysis; Spectrographic-analysis; Arsenic-compounds; Urinalysis; Selenium-compounds