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Mortality among employees of a perfluorooctanoic acid production plant.

Gilliland FD; Mandel JS

J Occup Med 1993 Sep; 35(9):950-954

https://doi.org/10.1097/00043764-199309000-00020

00217002

A study was conducted on the mortality rates of workers exposed to perfluorooctanoic-acid (335671) (PFOA). Workers at a chemical factory that produced PFOA were categorized as exposed or nonexposed, and the numbers of cause specific deaths were compared to expected numbers. The standardized mortality ratios for all causes of death for all women employees as well as for exposed women employees were significantly lower than expected. Similar results were seen for male employees. No associations were seen for male employees between any cause of death and length of employment. A standardized mortality ratio of 2.03 for prostate cancer was seen for exposed males compared with 0.58 for nonexposed males. A weak but significant positive association was seen between exposure and prostate cancer risk and the risk increased with length of employment. A positive association was seen as well between age at first employment and prostate cancer mortality.

JOCMA7; NIOSH-Publication; NIOSH-Grant; Training; Mortality-rates; Prostate-cancer; Surfactants; Fluorine-compounds; Occupational-exposure; Chemical-industry-workers

Environmental Health University of Minnesota 1158 Mayo Memorial Minneapolis, Minn 55455

JOCMA7

335-67-1

19930901

Journal Article

7317174

Grant

1993

Grant-Number-T15-OH-007098; Grant-Number-T42-OH-007098

9

0096-1736

Training

Journal of Occupational Medicine

MN

University of Minnesota of Mnpls-St Paul, Minneapolis, Minnesota