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Individual-administered human behavioral test batteries to identify neurotoxic chemicals.

Anger WK; Cassitto MG
Environ Res 1993 Apr; 61(1):93-106
The use of individual administered versus computer administered behavioral test batteries to describe worker exposure to neurotoxic chemicals was discussed. Individual administered test batteries were characterized as less efficient than computer administered batteries but much improved when aided by precision equipment. The use of the World Health Organization Neurobehavioral Core Test Battery to assess neurobehavioral function was based on the following: provision of a reference point for interstudy comparisons, inclusion of tests with proven sensitivity in all studies, and development of normative data for certain tests. The dominance of computer administered batteries was considered to be restrained by high initial cost, the need for computer service available only in highly industrialized countries, and the need to assess motor and sensory functions more difficult to measure with current computer hardware. The use of individual administered test batteries should address the following: the role of these batteries in screening chemically exposed working populations when computer administered batteries are dominant; the selection criteria to study the effects of known and unknown chemicals in humans; the usefulness of normative data for analysis and study interpretation; the need to validate these test batteries and to compare findings with unknown chemicals; availability of inexpensive test batteries for developing nations; and the equivalence of both forms of test administration with respect to variants of the same test.
NIOSH-Author; Behavioral-tests; Humans; Neurotoxicology; Analytical-methods; Medical-screening; Occupational-medicine; Sensory-motor-system; Behavioral-testing; Testing-equipment
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Journal Article
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Environmental Research
Page last reviewed: September 25, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division