This report described the efforts underway at NIOSH for the year 1990 in the areas of occupational safety and health. Some of the highlights during this time period occurred in the area of agricultural programs in which work was initiated on surveillance, research, and intervention in hazardous agricultural activities. Efforts in the area of construction provided assistance for identifying and evaluating occupational health risks to construction workers including mortality pattern analysis, identification of specific cancers linked to exposures on the job, and the role of asbestos (1332214) exposure in disease states. In the areas dealing with evaluation of reproductive risks from exposure to workplace toxicants, methods were developed for studying men for sperm profiling, and methods for adapting fertility indicators for assessing health effects for workplace exposures in women. Special attention was given to toluene-diisocyanate (584849) and toluene- diamine (496720). Bladder cancer was studied in workers occupationally exposed to ortho-toluidine (95534) and aniline (62533). Electrocution, one of the leading causes of traumatic occupational fatalities, was examined. A manual of analytical methods was published which contained additional information over the previous version.