A computerized data management system was described which provided systemic organization of occupational exposure information. The system was developed for an epidemiological study of workers exposed to acrylonitrile (107131) (AN). The employment histories of each study subject were abstracted and department and job titles were standardized. Air monitoring data and information on exposures were obtained during walk through surveys of operations involving AN handling, interviews with workers and supervisors, and company records. The computer system contained two exposure files: a Department Exposure Profile (DEP) including information common to all jobs within the department and a Job Exposure Profile (JEP) with information specific to the job. The first screen contained fields for job years, frequency, process, location, and tasks or duties, and also required input about the source of the information and confidence of its accuracy. Screen two, entered in the DEP file, had fields for entries about significant changes and unusual occurrences. Annual AN production rates and dates of routine overtime were entered in the DEP file on screen three. Screen four required the input of the frequency of exposure, health effects reported by the worker, and frequency of dermal exposure in both the DEP and JEP files. Screen five required information on the use of personal protective equipment and level of physical activity on both the department and job levels. Screen six required the entry onto the DEP level of a ranking of jobs within a department by AN exposure as well as other chemicals to which there was a risk of exposure in that department. Document control notebooks were developed to organize all of the information collected.