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Mortality of workers employed at organochlorine pesticide manufacturing plants - an update.
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, 1991 Jul; :1-27
A mortality study of workers at four organochlorine pesticide manufacturing factories was updated through 1987. The cohorts included all white male workers employed for at least 6 months before December 31, 1964 at the four factories. The workers had been exposed to the following organochlorine pesticides: chlordane (57749), heptachlor (76448), endrin (72208), aldrin (309002), dieldrin (60571), and dichlorodiphenyltrichloroethane (50293) (DDT). Workers at one factory had been exposed to the organobromine pesticide dibromochloropropane (96128). The total number of deaths for the period from 1976 through 1987 was 650. Mortality for all causes and all malignant neoplasms was lower that expected at each of the factories. Cerebrovascular disease mortality was elevated for three of the four factories. The most important result was the statistically significant increase in liver/biliary tract cancer among workers at the facility where aldrin and dieldrin were the primary organochlorine pesticides produced and the nonsignificant increase at the facility where DDT was manufactured.
NIOSH-Author; Pesticide-industry; Agricultural-chemicals; Occupational-exposure; Epidemiology; Cancer-rates; Risk-factors; Organo-chlorine-compounds; Mortality-data
57-74-9; 76-44-8; 72-20-8; 309-00-2; 60-57-1; 50-29-3; 96-12-8
Field Studies; Industry Wide
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: September 22, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division