A visible light fluorescent method was used to document areas of adriamycin (23214928) contamination on skin and work surfaces for pharmacists, pharmacy technicians, intravenous therapy administration personnel, oncology nurses, patient care nurses, maintenance workers, and hospital laundry workers. Monitoring for adriamycin exposure was conducted on 64 occasions. Adriamycin surface contamination was monitored in chemotherapy preparation areas, outpatient departments, biological safety cabinet filters, ventilation systems, laundry areas, and chemotherapy infusion equipment. Dermal exposures were not found among the staff members monitored, and no adriamycin contamination was found on any work surface. When adriamycin was applied to some materials and work surfaces, the ability to detect adriamycin fluorescence varied with the material and with concentration. Results indicated that fluorescence detection is sensitive, minimal equipment is needed, and very little training is needed to enable personnel to monitor their own work areas and skin. The authors suggest the method may be useful for industrial hygiene, dermal exposure, and surface contamination studies.
Field Screening Methods for Hazardous Wastes and Toxic Chemicals. Second International Symposium, February 12-14, 1991. Sponsored by U.S. EPA; U.S. DOE; U.S. Army Toxic and Hazardous Materials Agency; U.S. Army Chemical Research Development and Engineering Center; U.S.A.F.; Florida State Univ.; National Environmental Technology Applications Corp.; and NIOSH