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Immunological findings and respiratory function in cotton textile workers.
Zuskin-E; Kanceljak-B; Schachter-EN; Witek-TJ; Mustajbegovic-J; Maayani-S; Buck-MG; Rienzi-N
Int Arch Occup Environ Health 1992 Jun; 64(1):31-37
The immunological status of cotton textile workers was examined by skin testing with cotton dust and cotton seed extracts, bacteria, and fungi. Serum immunoglobulin-E (IgE) levels were also measured in 24 of the workers. The study cohort involved 83 women and 23 men in a community located on the coast of Yugoslavia. Of the 24 subjects undergoing immunological tests, eight had positive tests; five of these had elevated IgE levels but only one of the eight had symptoms of byssinosis. Only one of the 30 referents had a positive skin test and none had an increased IgE serum level. No differences were observed between workers with positive and negative skin test reactions or between workers with normal and elevated IgE levels in baseline lung function or across shift changes. The response of nonsensitized guinea-pig trachea to cotton bract extract was also examined, and demonstrated a dose dependent contractile response. The authors conclude that immunological findings, frequent in textile workers, correlated poorly with respiratory symptoms and function and may not be the basis for observed airway obstruction.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Textiles-industry; Textile-workers; Immune-reaction; Cotton-dust; Bacterial-dusts; Pulmonary-function; Allergic-reactions
Medicine Mount Sinai Medical Center One Gustave L Levy Place New York, N Y 10029
Issue of Publication
International Archives of Occupational and Environmental Health
Mount Sinai School of Medicine, New York, New York
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division