Epidemiologic studies of adverse reproductive outcomes in working populations.
Scand J Work, Environ & Health 1992 Jun; 18(Suppl 2):40-42
Some design issues common to epidemiologic studies on reproductive health in working populations were described, and new approaches in female reproductive studies were discussed. Basic information regarding reproductive toxicants to men in the workplace needs to be generated. Male reproductive epidemiologic studies have the ability to detect modest changes in the male reproductive profile. In one NIOSH study, over 50 measures of semen quality and hormonal levels were assessed. High participation rates have not been the norm for semen quality studies and unexposed groups were the least likely to participate. Pregnancy outcomes of women can contribute to the identification of a toxicant effect on fetal development or survival. Problems inherent in such studies as conducted in the United States include sample size, outcome definition and validation, tracing, and cooperation. New approaches in female reproductive studies were being evaluated including the feasibility of conducting a reproductive study of flight attendants who have multiple exposures of interest including ionizing and nonionizing radiations, alterations of circadian rhythm, and numerous airborne contaminants.
NIOSH-Author; Reproductive-hazards; Epidemiology; Reproductive-system-disorders; Radiation-exposure; Radiation-hazards; Aircrews; Occupational-exposure
Dr B Grajewski, Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, MailStop R15, Cincinnati, Ohio 45226-1998, USA
Scandinavian Journal of Work, Environment and Health