The Relationship between Blood Lead and Blood Pressure.
NIOSH 1992 Jan:37 pages
Epidemiologic studies on blood lead (7439921) and blood pressure in the general population and in occupationally exposed populations were reviewed. Six large population based surveys were conducted in Great Britain, Canada, Denmark, and the United States. In the population based studies, a small increase in blood pressure was associated with increases in blood lead. Increases in blood lead levels below 12 micrograms/deciliter (microg/dl) to levels higher than 25microg/dl were consistently accompanied by blood pressure increases in the range of 1.2 to 4mmHg diastolic blood pressure and 1.4 to 8mmHg systolic blood pressure. Occupational groups which have been studied due to their exposure to lead at the workplace include those in lead smelting, steel cutting, scrap metal recovery, battery manufacturing, lead pigment and lead soldered stained glass work, car repair, and police work. Although the results of the studies on occupational cohorts were mixed, they suggested a small positive association between blood lead and blood pressure. Methodologies used in the studies were critiqued. The authors recommend factors for future study.
NIOSH-Contract; Epidemiology; Lead-poisoning; Heavy-metals; Occupational-exposure; Blood-analysis; Foundry-workers; Environmental-exposure; Blood-pressure; Cardiovascular-system-disorders;
Final Contract Report;
NTIS Accession No.
Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, NIOSH Purchase Orders 91-39121 and 91-39188, 37 pages, 43 references