Exposure-response relationships for coal mine dust and obstructive lung disease following enactment of the federal coal mine health and safety act of 1969.
Seixas-NS; Robins-TG; Attfield-MD; Moulton-LH
Am J Ind Med 1992 May; 21(5):715-734
The exposure/response relationship between cumulative respirable coal mine dust exposure and indicators of obstructive lung disease was investigated in a group of miners who have been exposed only to the historically low concentration of dust present in the United States mines since the Coal Mine Health and Safety Act of 1969 took effect. The study cohort included 1185 miners participating in Round 4 of the National Study of Coal Workers' Pneumoconiosis. Using respirable dust measurements taken by the Mine Safety and Health Administration over the entire study period, quantitative estimates were made of cumulative exposure and were then used in linear and logistic regression models designed on indicators of pulmonary function and chest symptoms while controlling for smoking status, pack years, and other potential confounders. Statistically significant associations were found between log cumulative exposure and decrements in forced vital capacity (FVC), 1 second forced expiratory volume (FEV1), and FEV1/FVC. Statistically significant associations in the logistic models of cumulative exposure were found with increasing prevalence of FEV1 and FEV1/FVC less than 80% predicted and symptoms including chronic phlegm, chronic bronchitis, breathlessness, wheeze, and wheeze with shortness of breath were found. The authors conclude that exposures to respirable coal mine dust present in United States mines since 1970 continues to affect respiratory health in underground miners.
NIOSH-Publication; NIOSH-Author; NIOSH-Grant; Pulmonary-system-disorders; Coal-dust; Mineral-dusts; Dust-exposure; Respiratory-system-disorders; Lung-disease; Mining-industry; Coal-miners; Pulmonary-function-tests; Occupational-exposure
Environmental & Indust Health University of Michigan Dept of Envir/indust Health AN Arbor, MI 48109-2029
American Journal of Industrial Medicine
University of Michigan at Ann Arbor, Ann Arbor, Michigan