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Evaluation of respirator performance against aerosolized ribavirin in a health care setting.
Lenhart S; Decker J
Appl Occup Environ Hyg 1992 Apr; 7(4):216-217
A request for a health hazard evaluation was made by a respiratory therapist educator at a midwest medical center. The individual expressed concern over the effectiveness of procedures used at the hospital to control exposures of respiratory therapists and nurses to aerosolized ribavirin (36791045). Twelve inch cubical Care Cube disposal oxygen delivery hoods and Viratek Small Particle Aerosol Generators were used to administer the drug. Cubes were equipped with a scavenging system to limit the amount of released ribavirin. Results of simultaneous lapel and in mask sampling yielded average lapel concentrations ranging from 87 to 323 microgram/cubic meter (microg/m3). No detectable ribavirin was found in 59% of the in mask samples. All the respirators were high efficiency half masks. Estimated mask concentrations ranged from 0.6 to 1.1 microg/m3. The authors conclude that appreciable concentrations of aerosolized ribavirin were in the rooms where the drug was administered and that the respirators were sufficient. More detailed information on exposures, fit testing and protection factors, and recommendations are contained in Health Hazard Evaluation Report No . <a href="https://www.cdc.gov/niosh/hhe/reports/pdfs/1990-0155-2169.pdf"target="_blank">90-155-2169</a>.
NIOSH-Author; Health-care-personnel; Personal-protective-equipment; Respiratory-protective-equipment; Medical-treatment; Air-quality-monitoring; Nurses; Physicians; Author Keywords: 90-155-2169
NIOSH, Hazard Evaluation and Technical Assistance Branch, 4676 Columbia Parkway, Cincinnati, Ohio 45226
Issue of Publication
Applied Occupational and Environmental Hygiene
Page last reviewed: September 22, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division