Development of sampling and analytical methods for carcinogens.
Morales-R; Stampfer-JF Jr.; Hermes-RE; Campbell-EE; Ettinger-HJ
Los Alamos Scientific Laboratory, Los Alamos, New Mexico, 1978 Jul; :1-24
Monitoring 4-aminobiphenyl (92671), 4-nitrobiphenyl (92933), and 4- dimethylaminoazobenzene (60117) in air was described. Topics included: the generation and sampling of test atmospheres, development and evaluation of quantitative methods, evaluation of commercial respirator canisters, and determination of sampler efficiency. The system's sampling tubes were made of glass fiber filter and adsorbent beds for aerosol and vapor collection. Analyses were performed to microgram levels using gas chromatography with a flame ionization detector. Good resolution was obtained from possible contaminants. Respirator canisters used for protection against these specific chemicals were found to be satisfactory. The authors note that 4-aminobiphenyl and 4-nitrobiphenyl can be sampled and analyzed simultaneously. The analytical ranges were 0.2 to 50 micrograms/sample (microg/s), 0.2 to 110 microg/s, and 0.2 to 100 microg/s for 4-aminobiphenyl, 4-nitrobiphenyl, and 4- dimethylaminoazobenzene. Application of the sampling and analytical procedures to field conditions was considered.
NIOSH-Interagency-Agreement; Interagency-Agreement-76-52; Chromatographic-analysis; Analytical-methods; Air-quality-monitoring; Sampling-equipment; Biphenyls; Azo-compounds
92-67-1; 92-93-3; 60-11-7
NTIS Accession No.
Los Alamos Scientific Laboratory, Los Alamos, New Mexico, 24 pages, Interagency Agreement IA-76-52, 32 references