The effect of background variables on human peripheral lymphocyte micronuclei.
Complex mixtures and cancer risk. Vainio H, Sorsa M, McMichael AJ, eds. Lyon: International Agency for Research on Cancer, IARC Scientific Publications No. 104, 1990 Jan; :147-150
The possible influence of selected intrinsic and extrinsic factors on the cytokinesis block peripheral lymphocyte micronucleus assay was investigated. Analysis of micronuclei in peripheral blood lymphocytes using the cytokinesis block method was performed on healthy volunteers up to three times for each individual at intervals of approximately 4 months. Recent health and lifestyle information was obtained through the use of questionnaires. The findings indicated that age and estimated number of diagnostic X- rays received during the past year contributed significantly to the increased frequency of micronuclei. Linear regressions of log mean micronuclei on the average number of caffeinated beverages per day, number of cigarettes per day and average number of alcohol containing beverages per week were all nonsignificant.
NIOSH-Publication; NIOSH-Grant; Grants-other; Risk-factors; Age-factors; Radiation-exposure; Radiation-hazards; Blood-cells; Alcoholic-beverages; Cigarette-smoking
Biomedical & Environ Hlth Scis University of California School of Public Health Berkeley, CA 94720
Vainio H; Sorsa M; McMichael AJ
Complex mixtures and cancer risk
University of California Berkeley, Berkeley, California