Pleural determinants of restrictive lung function and respiratory symptoms in an asbestos-exposed population.
Broderick-A; Fuortes-LJ; Merchant-JA; Galvin-JR; Schwartz-DA
Chest 1992 Mar; 101(3):684-691
The relationship between pleural fibrosis and restrictive lung function was studied by measuring pulmonary function in sheet metal workers exposed to asbestos (1332214) containing materials. Workers employed in the trade for at least 25 years completed a questionnaire about work history, demographics, respiratory symptoms, asbestos exposure, and smoking. Subjects also received pulmonary function evaluations and chest X-rays. Pleural abnormalities were seen in 21.5% of the workers. Almost 17% had profusion ratings of 1/0 or more based on the International Labor Organization classification of X-rays. A significant relationship was seen between reduced forced vital capacity and circumscribed plaques, diffuse pleural thickening, costophrenic angle involvement, and the width and length of the pleural disease; the latter factors were also associated with dyspnea upon hurrying or walking uphill. Dyspnea while walking was related to diffuse thickening, involvement of the diaphragm and costophrenic angle, and length and width of the disease; chest pain was related to diffuse thickening, costophrenic angle involvement, and width of disease.
NIOSH-Grant; Pulmonary-system-disorders; Lung-fibrosis; Lung-lesions; Roofing-and-sheet-metal-work; Pulmonary-function; Occupational-exposure; Epidemiology; Asbestos-dust
Internal Medicine University of Iowa Pulmonary Disease Division Iowa City, IA 52242
Pulmonary System Disorders
University of Iowa, Iowa City, Iowa