Insecticide spraying in enclosed occupied areas.
JAMA J Am Med Assoc 1984 Oct; 252(13):1762
A question was presented which inquired about the safety of using bencarbate (22781233) and chlorpyrifos (2921882) for insect control in hospitals in areas that are occupied by patients and workers alike. The answer provided noted that in many states the practice of applying pesticides in occupied areas is prohibited by regulations. Both the mentioned compounds were noted to be of moderate acute toxicity. While both were noted able to inhibit cholinesterase activity, cholinesterase determinations are not likely to be helpful in the case of the incidental exposures to pesticides in this situation. These exposures are likely low and the experienced headaches, impaired memory and concentration, and behavioral effects are associated with low levels of organophosphate exposure. For most pesticides adequate investigations of allergenic potentials have not been undertaken, but some organophosphates can cause dermal sensitization and upper respiratory tract irritation.
NIOSH-Author; Organo-phosphorus-compounds; Neuropathology; Organo-phosphorus-pesticides; Carbamates; Enzyme-activity; Pest-control; Nervous-system-disorders; Indoor-air-pollution; Insecticides; Indoor-environmental-quality
Journal of the American Medical Association