NIOSHTIC-2 Publications Search
Recent studies of temporary threshold shift (TTS) and permanent threshold shift (PTS) in animals.
J Acoust Soc Am 1991 Jul; 90(1):155-163
A review was presented to describe the major observations obtained from laboratory studies of experimentally induced hearing losses, both temporary and permanent, resulting from exposure to noise in animal subjects. Studies that measured hearing directly were given the greatest weight in the review. The data evaluated supported several general conclusions. The chinchilla was the most widely used and most appropriate animal model for studies of noise induced hearing loss. With continuous exposures to moderate level noise, thresholds reached asymptotic levels within 18 to 24 hours. Permanent threshold shifts, however, depended upon the level, frequency, and the duration of exposure. Below a critical level of about 115 decibels, permanent threshold shift and cell loss were generally related to the total energy in continuous exposures. Periodic rest periods inserted in an exposure schedule were predictive and resulted in less hearing loss and cochlear damage than equal energy continuous exposures. Under some schedules of periodic exposure, threshold shifts increased over the first few days of exposure, then recovered as much as 30 decibels as the exposure continued.
NIOSH-Publication; NIOSH-Grant; Acoustical-measurements; Acoustic-vibration; Hearing-loss; Noise-exposure; Noise-induced-hearing-loss; Hearing-impairment; Ear-disorders; Sensory-thresholds
Research Central Inst for the Deaf 818 South Euclid St Louis, MO 63110
Issue of Publication
Journal of the Acoustical Society of America
Central Institute for the Deaf, Saint Louis, Missouri
Page last reviewed: October 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division