NIOSHTIC-2 Publications Search

Artificial intelligence-assisted occupational lung disease diagnosis.

Harber P; McCoy JM; Howard K; Greer D; Luo J

Chest 1991 Aug; 100(2):340-346

https://doi.org/10.1378/chest.100.2.340

00201680

The development and pilot application of an artificial intelligence expert system to help clinicians recognize occupational factors in lung disease were described. The system was operable on IBM PC compatible microcomputers. The method of integrating epidemiologic knowledge and clinical data was illustrated. Development of the system required explicitly determining the types of information and the process by which knowledge is used in establishing such diagnoses. The system used a knowledge representation scheme to capture relevant clinical knowledge into structures about specific objects and pairwise relations between objects. Quantifiers described both the closeness of association and risk, as well as the degree of belief in the validity of a fact. An independent inference engine used the knowledge, combining likelihoods and uncertainties to achieve estimates of likelihood factors for specific paths from work to illness. The system created a series of paths, linking work activities to disease outcomes. One path linked a single period of work to a single possible disease outcome. In a preliminary trial, the number of paths from job to possible disease averaged 18 per subject in a general population and averaged 25 per subject in an asthmatic population. The authors conclude that artificial intelligence methods hold promise in the future to facilitate diagnosis in pulmonary and occupational medicine.

NIOSH-Publication; NIOSH-Grant; Risk-factors; Occupational-exposure; Disease-incidence; Respiratory-system-disorders; Lung-disease; Diagnostic-techniques; Occupational-respiratory-disease

Medicine University of California School of Medicine Los Angeles, Calif 90024

CHETBF

19910801

Journal Article

654363

Grant

1991

Grant-Number-R01-OH-002005

2

0012-3692

Respirators

Chest

CA

University of California Los Angeles, Los Angeles, California