Indirect fertility analysis in painters exposed to ethylene glycol ethers: sensitivity and specificity.
Welch-LS; Plotkin-E; Schrader-S
Am J Ind Med 1991 Aug; 20(2):229-240
Th sensitivities of a questionnaire method were compared with those of semen analysis in an evaluation of reproductive function in men exposed to ethylene-glycol (107211) ethers. The questionnaire method determined the number of births to wives of male workers for comparison with expected numbers. Reproductive function of 74 married painters employed at a large shipbuilding facility was compared with that of 51 married comparisons employed at the same shipyard, using both semen analysis and the questionnaire method. Comparisons were selected from clerks and marine draftsmen, who generally had no work aboard ships. The exposed and comparison groups differed in sperm count, but the questionnaire method showed no effect of exposure on fertility. When exposed painters were compared with their own preemployment history, there was no significant difference in fertility. Preemployment fertility for comparisons was higher compared with fertility after employment. The findings suggested that the questionnaire assessment of fertility is less sensitive than the semen analysis method as a screening tool for male reproductive function.
NIOSH-Author; Solvents; Reproductive-system-disorders; Reproductive-hazards; Epidemiology; Occupational-exposure; Shipbuilding-industry; Spermatogenesis
American Journal of Industrial Medicine