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Cancer mortality among silicotic cases.

Rubino-GF; Scansetti-G; Piolatto-G; Coggiola-M; Giachino-GM
Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 90-108, 1990 Nov; (Part II):1509-1513
An investigation was conducted to ascertain whether a cancer mortality excess, particularly from lung cancer, exists among workers exposed to silica (7631869). The Archives of Turin office of the National Institute of Insurance were examined and the clinical documentation was collected for each male worker who received compensation for silicosis and died between 1970 and 1983; for a total of 746 subjects. A lung cancer mortality excess was observed with 81 cases being observed against the 59.5 cases expected. A high mortality rate of 27.8% related to silica dust exposure was also revealed. Observed and expected deaths related to specific causes were arranged according to exposure in the different working activities: miners, foundry workers and employees in other industrial fields such as glass manufacturing, potting and brick works. The enhanced mortality risk for pulmonary neoplasm did not appear related to silicotic risk. An increased risk was not present in the group of underground workers and a significant excess of lung cancer was present in the group of foundry workers rated at low silica exposure. The authors conclude that in foundries risk factors other than silica are present and can play at least a complimentary role in the establishment of pulmonary cancer.
Respiratory-system-disorders; Mining-industry; Epidemiology; Lung-disease; Cancer-rates; Mortality-rates; Lung-cancer; Risk-factors
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DHHS (NIOSH) Publication No. 90-108
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Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA