A Case Study on Fiberglass Pneumoconiosis with Undifferentiated Cancer - Fiberglass, Cancerogenous Material.
NIOSH 1990 Nov:1395-1397
A case of fiberglass pneumoconiosis, diagnosed at autopsy, was presented. The victim, a 65 year old male, had been exposed to fiberglass from 1939 through 1949 in his occupation. Death occurred in 1957. The use of fiberglass as a substitute for asbestos (1332214) has been increasing. Yet it was noted that long term inhalation of dust and its sustained deposit in alveoli can cause pneumoconiosis of various types whether the dust is insoluble, scarcely soluble or soluble. The foreign body reaction or inflammation was defined as the process during which the action of phagocytes and the cell proliferation containing fibroblasts and fibrocytes occur, resulting in cell degeneration and fibrosis of various grades. The author concludes that the fundamental and common cause of pneumoconiosis is the inflammatory changes of the lung to excessive dusts as foreign matters. He also states that every kind of dust is active and every pneumoconiosis is harmful. There is no inert dust and no benign pneumoconiosis.
Lung-disease; Postmortem-examination; Lung-cells; Dust-inhalation; Dust-exposure; Airborne-particles; Lung-irritants; Fiberglass-industry;
DHHS (NIOSH) Publication No. 90-108
Proceedings of the VIIth International Pneumoconioses Conference