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Time domain spirogram indices of silica exposed workers.

Chia-KS; Ng-TP; Jeyaratnam-J
Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 90-108, 1990 Sep; (Part I):511-517
An experiment was performed which applied the various spirometric indices as well as time domain indices on a group of granite quarry workers to evaluate their small airways function in relation to their dust exposure. The volume time spirograms of 132 currently employed granite quarry workers were selected. There were 50 nonsmokers and 60 smokers in the study population. The results suggested that small airway obstruction was present among silica (14808607) exposed workers in the absence of radiological evidence of silicosis. There was also evidence of a trend of increasing small airways obstruction in higher dust exposure groups. Smokers revealed greater evidence of small airways obstruction even after excluding those with evidence of significant airway obstruction. The amount of cigarettes smoked was not significantly different in the three groups. Thus the trend of small airways obstruction in smokers suggested the effect of silica exposure. The results also suggested that time domain indices were more sensitive to small airways obstruction. The authors state that these indices give greater emphasis to the end of the forced expiratory maneuver and are therefore more sensitive to events in the small airways.
Diagnostic-techniques; Mineral-dusts; Respiratory-system-disorders; Lung-disease; Quarry-workers; Cigarette-smoking; Pulmonary-function-tests; Radiographic-analysis; Airway-resistance
Publication Date
Document Type
Conference/Symposia Proceedings
Fiscal Year
Identifying No.
DHHS (NIOSH) Publication No. 90-108
Source Name
Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division