Silicosis and lung cancer: preliminary results from the California Silicosis Registry.
Goldsmith-DF; Beaumont-JJ; Lutzenhiser-S; Schenker-MB
Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 90-108, 1990 Sep; (Part I):421-425
A preliminary assessment was presented of the proportionate mortality risk for silicosis claims and confirmed the results of an elevated risk for pulmonary cancer. As these results are preliminary and only represent a minority of cases expected to be in the registry when it is completed, some caution was advised in drawing definitive conclusions. In the United States there were noted to be over 3,000,000 workers exposed to silica (14808607) and over 100,000 suffering from silicosis. The authors urge that physicians who now care for silicosis patients become aware of the consistent observation of excess lung cancer risk and transmit this information to their patients; that occupational health agencies reexamine the current standards for silica and factor in the consequences of its being labeled as a probable human carcinogen; and that additional research be conducted among silica exposed workers to prevent new cases of fibrotic lung disease and assess their risk for cancer in the absence of silicosis.
Epidemiology; Silica-dusts; Dust-inhalation; Respiratory-system-disorders; Pulmonary-function-tests; Risk-factors; Mortality-data; Carcinogenesis; Cancer-rates
DHHS (NIOSH) Publication No. 90-108
Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA