NIOSHTIC-2 Publications Search
Assessing exposure to 4,4'-methylene bis(2-chloroaniline) (MBOCA) in the workplace.
Clapp-DE; Piacitelli-GM; Zaebst-DD; Ward-E
Appl Occup Environ Hyg 1991 Feb; 6(2):125-130
Environmental exposure measurements were compared with biomonitoring results for worker exposure to 4,4'-methylene-bis(2-chloroaniline) (101144) (MBOCA). A study of occupational exposures to MBOCA was conducted at a Midwestern company that manufactured commercial polyurethane products and was a large user of MBOCA. The process studied was the manufacture of MBOCA cured urethane elastomer and its subsequent molding in the molding area of the Urethane Department. Dry MBOCA pellets were received at the site and transferred by hand to a melting pot. An isocyanate prepolymer was used to form a moldable urethane prior to pouring into the molds. The greatest potential for exposures occurred when workers directly contact MBOCA or surfaces contaminated with MBOCA. This generally involved workers required to work in areas where MBOCA was stored, transferred, mixed, or melted, and who may not regularly wear gloves or whose gloves were prone to puncture and tearing. Even exposure to relatively low levels of contamination could result in substantial absorbed doses. The authors recommend that biological monitoring, rather than environmental sampling, be used to serve as an indicator of occupational exposure to MBOCA.
NIOSH-Author; Plastics-industry; Occupational-exposure; Biological-monitoring; Protective-clothing; Air-quality-monitoring; Urinalysis; Carcinogens; Anilines
Issue of Publication
Applied Occupational and Environmental Hygiene
Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division