Evidence for behavioral teratogenicity in humans.
J Appl Toxicol 1991 Feb; 11(1):33-37
A brief review was presented of accumulated evidence that prenatal exposure to a number of chemical agents produced behavioral disorders in human beings. Topics included: the incidence of mental retardation, developmental disabilities, psychological disorders, learning disabilities, and birth defects; behavioral disfunctions; established, probable and suspected human behavioral teratogens; testing of new drugs; and exposure of pregnant women to environmental and industrial chemicals. Although many drugs and environmental and industrial agents have been shown to produce behavioral teratogenicity in humans, the etiology of the vast majority of human developmental disorders has been unknown. The author concludes that the existence of childhood disorders and dysfunctions, accompanied by a lack of knowledge concerning the etiology of these disorders, demonstrates the need for additional research in the field of developmental neurotoxicology.
NIOSH-Author; Reproductive-system-disorders; Teratogenesis; Developmental-disorders; Environmental-pollution; Neonates; Embryotoxicity; Reproductive-hazards; Nervous-system-disorders; Brain-damage; Neurotoxicology;
Author Keywords: behavioral teratology; teratology; developmental toxicology; developmental neurotoxicology; behavioral disorders; mental retardation; hyperactivity; reproductive toxicology; children; pregnancy
B. K. Nelson, Division of Biomedical and Behavioral Science, NIOSH C-24. 4676 Columbia Parkway, Cincinnati, OH 45226, USA
Journal of Applied Toxicology