A proposed national strategy for the prevention of psychological disorders was presented. Both occupational and nonoccupational factors enter into the development of psychological disorders among workers. Psychological disorders of current interest include affective disturbances such as anxiety, depression, and job dissatisfaction; maladaptive behavioral and lifestyle patterns; and chemical dependencies and alcohol abuse. At this time no surveillance system exists to adequately gauge the national scope of psychological health disorders. Epidemiologic and health care data on costs are accumulating, however. The prevention of work related psychological disorders includes better job design to improve working conditions, surveillance of psychological disorders and risk factors, information gathering and dissemination, training and education of workers, and the enrichment of psychological health services for workers. Recommendations for controlling psychosocial risk factors at work; for improving surveillance of work related psychological disorders and risk factors; for information dissemination, education, and training; and for improving worksite based mental health services are presented.