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Comparison of serum levels of 2,3,7,8-TCDD in TCP production workers and in an unexposed comparison group.
Sweeney MH; Fingerhut MA; Patterson DG Jr.; Connally LB; Piacitelli LA; Morris JA; Greife AL; Hornung RW; Marlow DA; Dugle JE; Halperin WE; Needham LL
Chemosphere 1990; 20(7-9):993-1000
The results of the analysis of 197 serum samples for 2,3,7,8- tetrachlorodibenzo-p-dioxin (1746016) (TCDD) were reported. These samples were taken from 143 workers and 54 unexposed referents in the New Jersey and Missouri cohorts. Workers in this analysis were employed at either of two facilities located in Newark, New Jersey or Venona, Missouri. Both facilities produced sodium- trichlorophenol (1320792) and 2,4,5-trichlorophenoxyacetic-acid (93765). The mean serum TCDD level for all workers was 251.7 parts per trillion (ppt) and for all referents combined it was 7.8ppt. The mean level of TCDD present in the serum of workers at the date of termination of exposures was 2,600ppt and 870ppt for the New Jersey and Missouri workers, respectively. The levels in the workers were correlated significantly with the duration of exposure to the TCDD contaminated processes.
NIOSH-Author; Chemical-industry-workers; Chlorinated-hydrocarbon-pesticides; Environmental-contamination; Occupational-exposure; Blood-serum; Agricultural-chemicals; Blood-analysis; Author Keywords: Cross-sectional medical study; occupational exposure; serum 2; 3; 7; 8-TCDD levels; dioxin
1746-01-6; 1320-79-2; 93-76-5
Issue of Publication
MO; NJ; GA; OH
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division