This testimony presented the views of NIOSH regarding worker exposure to ethylene-dibromide (106934) (EDB). Approximately 108,000 workers in the United States were potentially exposed to EDB during its production and use. An additional 875,000 workers were potentially exposed to EDB while working with leaded gasoline. EDB may enter the body through inhalation or skin contact. Little information was available concerning the results of long term exposures. Animal studies have demonstrated mutagenic effects, reproductive abnormalities, cancers of the stomach, skin tumors, testicular degenerative changes, and tumors at several body sites resulting from EDB exposure. Existing regulations pertinent to EDB were reviewed. NIOSH has recommended the use of engineering controls, workplace monitoring, the use of labeling and warning signs where EDB is used, the use of personal protective equipment, and medical surveillance of exposed workers. NIOSH continues to be very concerned about EDB and will continue to evaluate the data to make those recommendations which are prudent for worker protection.