Proceedings of the International Conference on Bladder Cancer Screening in High-Risk Groups, September 13-14, 1989.
Proceedings from the International Conference on Bladder Cancer Screening in High Risk Groups were provided. A general discussion was presented on the role of medical screening for prevention of occupational diseases, delineation of the problem, the pathology and attendant problems of bladder cancer, and national estimates of occupational exposure to animal bladder tumorigens. Detection techniques were examined and included intervention trials, urine cytology, quantitative fluorescence image analysis, flow cytometry detection, cystoscopy and bladder mucosal biopsy, hematuria screening, evaluation of urinary autocrine motility factor and tumor cell collagenase stimulating factor, and molecular and cellular biological approaches. A critical review of screening programs was provided through the presentation of current investigations for bladder cancer screening and their results. Research on detection methods included voided urine flow cytometry, evaluation of DNA flow cytometry, use of the epithelial surface marker epithelial membrane antigen, use of monoclonal antibodies for the detection of exfoliated bladder cancer cells, and acetylation phenotypes. The therapeutic potential of current therapy for bladder cancer and survival statistics were also discussed.