National estimates of occupational exposure to animal bladder tumorigens.
Ruder AM; Fine LJ; Sundin DS
J Occup Med 1990 Sep; 32(9):797-805
An evaluation was presented of the Registry of Toxic Effects of Chemical Substances from NIOSH which has identified nearly 200 substances which are associated with animal bladder tumors. Information contained in the National Occupational Exposure Survey and the National Occupational Hazard Survey indicated that the number of workers with full time (greater than 4 hours per day) occupational exposures to these chemicals was about 60,000 in the early 1970s and about 700,000 by the early 1980s. The lists also indicated about 1.8 million workers had some occupational exposure in the 1970s and 3.5 million in the 1980s. The figures were to be noted somewhat inaccurate because some of the animal tumorigens may not be human carcinogens and the estimates were based on potential rather than measured exposures. The authors conclude that the risk would depend on the potency, duration and intensity of the actual exposures. Even so, these estimates are useful in estimating the approximate magnitude of the potential occupational exposure to animal bladder tumorigens.
JOCMA7; NIOSH-Author; Risk-factors; Risk-analysis; Carcinogenesis; Tumorigenesis; Epidemiology; Industrial-hazards; Bladder-cancer; Bladder-disease
Journal of Occupational Medicine