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The effects of inorganic lead on behavioral and neurologic function. Final report.
Repko-JD; Corum-CR; Jones-PD; Garcia-LS Jr.
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 78-128, 1978 Jan; :1-102
Subjects in this study of the effects of lead (7439921) exposure on behavioral and neurologic function were employed in two regions of the United States. Of the 140 workers sampled, 85 workers were exposed to lead in the job and 55 served as comparisons. Each worker who volunteered for the study was subjected to 53 behavioral measures of sensory and motor functioning, six measures of nerve conduction velocity, five indices of inorganic lead absorption, a clinical electromyogram, and a clinical neurological examination. Demographic data were also collected from each participant. The exposed workers were employed in the storage battery manufacturing industry. Based on the data obtained in this study and others, the adverse effects of occupational exposure to inorganic lead (7439921) on certain functional capacities was demonstrated. Quantifiable behavioral and neurological effects were noted at levels below the accepted biologic guideline of 80 micrograms of lead per 100 milliliters of blood. Deficits in the peripheral nerves, in visual reaction time, as well as deficits in auditory functioning were demonstrated. According to the authors, questions concerning the progression of these effects and their reversibility in individual workers must be addressed.
NIOSH-Contract; Contract-210-75-0054; Nervous-system-disorders; Neuropathology; Lead-poisoning; Behavioral-disorders; Battery-manufacturing-industry; Heavy-metals; Toxic-effects
NTIS Accession No.
DHEW (NIOSH) Publication No. 78-128; Contract-210-75-0054
National Institute for Occupational Safety and Health
Page last reviewed: March 11, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division