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Letter to the editor. Oligospermia in workers exposed to methylene chloride.
Wells-VE; Schrader-SM; McCammon-CS; Ward-EM; Turner-TW; Thun-MJ; Halperin-WE
Reprod Toxicol 1989 Oct; 3(4):281-282
An investigation of oligospermia among furniture strippers exposed to methylene-chloride (75092) was carried out. Data were collected on 11 men. Results on the levels of carboxyhemoglobin for smokers and nonsmokers were 3.9 and 10.2 percent, respectively. These levels were notably higher than the 2 percent standard upper limit for nonsmoking individuals. The mean time/weighted average for methylene-chloride exposure which was determined to be 122 parts per million (ppm) was greater than the lowest feasible limit suggested by NIOSH, although it was below the current 500ppm OSHA standard. Sperm concentration data exhibited an average of 54 million per cubic centimeter (m/cc) which was greater than the 47m/cc average of a group of nonexposed workers previously examined. This average for exposed individuals was also noted to be significantly higher than the 20m/cc level, below which usually defines oligospermia. The authors suggest that the results are limited due to the small population examined. However, it was noted that none of the methylene-chloride exposed individuals examined had oligospermia.
NIOSH-Author; Occupational-exposure; Furniture-workers; Exposure-levels; Organo-chlorine-compounds; Workplace-studies; Exposure-limits; Reproductive-system-disorders
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Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division