Cumulative asbestos exposure and forced vital capacity.
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 1975 Jan; :1-19
Part of the data from a retrospective study of asbestos (1332214) textile workers was used to relate loss in forced vital capacity (FVC) to cumulative asbestos exposure. Using occupational histories and the results of air sampling analyses, estimates of individual cumulative asbestos fiber exposures were made for asbestos textile workers. Only those workers with more than 10 years of exposure were included in the analysis. The patterns of exposure in the production workers indicated high exposures in the 1930s, dramatic reductions in the late 1930s to early 1940s, and some further reduction to about 1950 with little change thereafter to the conclusion of the study. A relationship was developed between the ratio of the observed forced vital capacity to predicted forced vital capacity and the logarithm of exposure by linear regression. Tests were also made using office workers in the same textile facility. Weavers and yarn production workers had forced vital capacities which were less than the predicted values and less than those of the office workers. A progressive effect was noted of asbestos dust exposure on forced vital capacity. Each doubling of cumulative asbestos fiber exposure above 100 fiber years/cubic centimeter resulted in a loss of 5 to 10 percent in forced vital capacity.
NIOSH-Author; NIOSH-Grant; Training; Asbestos-workers; Textile-workers; Occupational-exposure; Asbestos-fibers; Pulmonary-system-disorders; Lung-function; Pulmonary-function-tests
Environmental Health Kettering Laboratory College of Medicine Cincinnati, Ohio 45219
Final Grant Report
NTIS Accession No.
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio
University of Cincinnati, Cincinnati, Ohio