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Carbon monoxide and human functions.
Beard RR; Grandstaff NW
Department of Community and Preventive Medicine, Stanford University, Stanford, California 1972 Jun; :1-35
The effects of low concentrations of carbon-monoxide (630080) (CO) on several aspects of cerebral functions in man were examined. These functions included perception, discrimination, memory and complex cognitive processes. The study participants included healthy young male and female Stanford students between ages 18 and 25 years. Each subject was exposed to CO in a chamber from which the air was continuously sampled. CO concentrations were 50, 175, or 250 parts per million. Each daily test session consisted of four rounds of 40 minutes each, divided into a 25 or 20 minute test period and a 15 or 20 minute rest period. Vigilance was significantly reduced and the performance of a given task involving estimation of time and motion together was also compromised. Only marginal impairment was noted in a complex problem solving test. No consistency or reliability was discerned in the effects on spatial perception, digit span, or arithmetic performances.
NIOSH-Grant; Neurotoxic-effects; Task-performance; Work-capability; Toxic-gases; Humans; Toxic-effects
Preventive Medicine Stanford University Sch of Med Stanford, Calif 94305
Final Grant Report
NTIS Accession No.
Department of Community and Preventive Medicine, Stanford University, Stanford, California
Stanford University, Stanford, California
Page last reviewed: February 18, 2022
Content source: National Institute for Occupational Safety and Health Education and Information Division