NIOSHTIC-2 Publications Search
Particulate concentrations in urban lungs.
Stettler-LE; Groth-DH; Platek-SF; Burg-JR
Microprobe Analysis in Medicine 1989:133-146
Particle contents of 92 left lungs from deceased residents of the Cincinnati, Ohio area were being determined by NIOSH; results of preliminary findings for 33 of these samples were reported. The ages of the deceased ranged from 23 to 96 years. Thirty seven were nonsmokers. The occupations of this group included foundry worker, machinist, farmer, gardener, salesman, domestic worker, waitress, clerical worker, and homemaker. Deaths were from normal causes, mostly chronic degenerative conditions of advancing age. Some had acute disease conditions, but none died traumatically. The exogenous particle concentrations for the 33 lungs analyzed thus far ranged from 107 million to 1609 million particles per gram of dry lung. In none of these lungs was there evidence of an overt pneumoconiosis. The automated scanning electron microscopy-energy dispersive x-ray analysis/image analysis procedure was used for these analyses and has the primary advantage of speed with which particles may be analyzed. The data presented were collected at the rate of about 300 particles per hour. One disadvantage was that using ashed lung preparations may mean that information concerning the specific location of the particles in the lung tissue may be lost.
Analytical-methods; Lung-burden; Tissue-distribution; Pulmonary-system-disorders; Airborne-particles; Lung-disorders; Lung-disease; Humans
Ingram-P; Shelburne-JD; Roggli-VL;
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Pulmonary-system-disorders
Microprobe Analysis in Medicine
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division