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Information profiles on potential occupational hazards: glycols.
Center for Chemical Hazard Assessment, Syracuse Research Corporation, Syracuse, New York, 1982 Feb; :1-208
Based on their importance in the industrial community, information profiles were provided for the following glycols: 2-butene-1,4-diol (110645), 1,3-butylene-glycol (107880), 1,4-butylene-glycol (110634), 2-butyne-1,4-diol (110656), 1,4-cyclohexanedimethanol (105088), diethylene-glycol (111466), dipropylene-glycol (108612), ethylene-glycol (107211), 2-ethyl-1,3-hexanediol (94962), 1,6- hexanediol (629118), 2,5-hexanediol (2935446), 2-methyl-2-propyl-1,3- propanediol (78262), neopentyl-glycol (126307), 1,5-pentanediol (111295), propylene-glycol (57556), tetraethylene-glycol (112607), triethylene-glycol (112276), 2,2,4-trimethyl-1,3-pentanediol (144194), and tripropylene-glycol (1638160). The acute toxicity of these compounds was characterized by central nervous system depression. Some of the glycols have caused renal damage of varying degrees. Some of the glycols were readily absorbed through the skin. Administration of diethylene-glycol to animals has caused formation of bladder stones. Investigation of possible carcinogenic, teratogenic, reproductive, or mutagenic potentials for these compounds had been very limited.
NIOSH-Contract; Contract-210-79-0030; Agricultural-chemicals; Electroplating; Plasticizers; Resins; Corrosion-inhibitors; Explosives; Toxic-effects; Nervous-system-disorders; Kidney-damage
110-64-5; 107-88-0; 110-63-4; 110-65-6; 105-08-8; 111-46-6; 108-61-2; 107-21-1; 94-96-2; 629-11-8; 2935-44-6; 78-26-2; 126-30-7; 111-29-5; 57-55-6; 112-60-7; 112-27-6; 144-19-4; 1638-16-0
Final Contract Report
NTIS Accession No.
Center for Chemical Hazard Assessment, Syracuse Research Corporation, Syracuse, New York, 208 pages, 206 references
Page last reviewed: June 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division