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Review and evaluation of recent scientific literature relevant to an occupational standard for ethylene dibromide.
Atlanta, GA: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Contract 210-78-0009, 1979 Nov; :1-66
This report served as a critical review and evaluation of recent literature concerning hazards associated with exposure to ethylene- dibromide (106934). Workers exposed to ethylene-dibromide may experience severe acute respiratory damage, central nervous system depression, and severe vomiting on inhalation of the vapors. Skin contact can cause erythema, blistering, and ulceration. A recommended ceiling level for occupational exposures has been set by NIOSH at 1mg/m3. NIOSH has identified the following areas as needing future research: epidemiological surveys, liver and kidney function tests, and biological monitoring among exposed workers. It was also recommended that animal studies be conducted with regard to possible carcinogenic, mutagenic, and teratogenic effects. Other specific areas covered in the review included the results of animals studies already conducted in the areas of carcinogenicity, mutagenicity, reproductive effects, developmental effects, hepatic effects, metabolic studies, synergistic effects, general toxicity, work practices, engineering controls, sampling and analytical methods.
NIOSH-Contract; Contract-210-78-0009; Fumigants; Pulmonary-system-disorders; Central-nervous-system-disorders; Irritants; Laboratory-animals; Personal-protective-equipment; Inhalants; Skin-exposure; Occupational-exposure; Toxic-effects
Final Contract Report
NTIS Accession No.
National Institute for Occupational Safety and Health
Syracuse Research Corporation, Center for Chemical Hazard Assessment, Syracuse, New York
Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division