Preliminary Report on a Case-Control Study of Cancers of the Lung, Stomach, and Pancreas in Southern Louisiana.
Correa-P; Pickle-LW; Fontham-ET; Johnson-WD
NIOSH 1982 Apr:67-88
Preliminary results of a case/control study of lung, stomach, and pancreatic cancer in southern Louisiana were presented. The cohort consisted of 1842 cases of primary lung cancer, 319 cases of stomach cancer, and 229 cases of pancreatic cancer diagnosed since 1979 in the residents of 26 parishes in southern Louisiana. The referents consisted of 1434 persons matched by hospital, race, sex, and age to the lung cancer cases, 174 persons similarly matched to the pancreatic cancer cases, and 232 persons matched to the stomach cancer cases. The relative risk for lung cancer and its dependency on smoking habits were calculated. The relative risk for stomach cancer as a function of dietary intake of vitamin-C and vitamin-A was determined. The relative risk of pancreatic cancer as a function of coffee consumption was determined. Only 3.2 percent of the lung cancer cases reported not using tobacco versus 22.8 percent of the referents, and 70.3 percent of the cases reported smoking only cigarettes versus 47.6 percent of the referents. Approximately 88 percent of the lung cancer cases who were ever smokers smoked at least one pack of cigarettes per day versus 74 percent of the referents. Twice as many cases smoked three packs of cigarettes per day as the referents. Although use of filter and nonfilter cigarettes did not differ significantly between the cases and referents, nearly twice as many referents switched from nonfilter to filter cigarettes before the age of 30. The relative risk for lung cancer for those who started smoking before the age of 16 was 1.54. The stomach cancer cases had lower dietary intakes of vitamin-A and vitamin-C than the referents. Daily consumption of five or more cups of coffee was associated with a slight, nonsignificant risk of pancreatic cancer, relative risk 1.3. A transcript of a discussion session following the presentation was included.
Epidemiology; Lung-cancer; Stomach-cancer; Cigarette-smoking; Risk-factors; Dietary-effects; Risk-analysis; Vitamins; Nutrition; Humans;
Proceedings of the Second NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies, September 9-11, 1981, Rockville, Maryland