Progress in a study of possible teratogenic and carcinogenic effects of pesticides used in Colombia was reported. The primary activities being reported included a census taken of workers in floriculture, formulating facilities and sanitary campaigns in Colombia; the preparation of a final version of a questionnaires to be used in the teratogenesis phase of the work; a site visit to the National Institute of Health in Bogota; a meeting of the principles involved in the research; and the recruitment and training of interviewers. A total of 39 of the 44 enterprises identified through the census agreed to participate in the study. The number of workers in these companies with possible pesticide exposure was 13,000 with about 86 percent being between the ages of 15 and 40 years. Among the several job classifications at each facility were sorters, thinners, pruners, packers, cutters, mixers, fumigators, rubber band applicators, and packers. A list of substances used at the facilities was being obtained. The visit to the National Health Institute underlined the advantages to this particular study group as being large in number, containing most workers in the reproductive age, the fact that a wide range of pesticides is used, and that the companies are willing to cooperate. Rapid turnover of workers was seen as a drawback to the study. The most commonly used pesticides in this area include captan (133062), mancozeb (8018017), sodium-metham (137428), and propineb (12071839). The study calls for the analysis of blood where appropriate for plasma cholinesterase, red cell cholinesterase, organochlorine pesticides and metabolites and intact organophosphorus pesticides. Urine will be analyzed for creatinine, and pesticide metabolites.
Proceedings of the Second NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies, September 9-11, 1981, Rockville, Maryland