The consistent occurrence of a striated organelle (Friedmann body) in the inner hair cells of the normal chinchilla.
Slepecky-N; Hamernik-R; Henderson-D
Acta Oto-Laryngol 1981 Feb; 91(1-2):189-198
The consistent occurrence of the striated bodies in the inner hair cells of normal chinchillas was reported. Both cochleas from ten normal chinchillas 1 to 7 years of age were examined. In all cases for the over 70 inner hair cells sectioned, when serial sections were examined, striated bodies were found to be located in every inner hair cell. Striated bodies were not observed in the outer hair cells even though three times as many outer hair cells were examined. Striated bodies were found below the cuticular plate when the organ of Corti was sectioned in a radial plane parallel with the long axis of the hair cells. In the radial plane the striated body is composed of electron dense bands, separated by spaces of less electron dense material. The striated body is at times separated from the cuticular plate and may be surrounded on both top and bottom surfaces by cytoplasm and endoplasmic reticulum. The lack of earlier reports of striated bodies in chinchilla hair cells probably stems from the difficulty of detection which requires observation made through serial sections. While the role of the striated organelle in the inner hair cell is not known, it may have some significance to the mechanical stimulation of the stereocilia which is the first step in the transduction process. The striated organelle could play a passive role in maintaining the cytoarchitecture of the inner hair cell. It may also be active by controlling the interaction of contractile proteins.
NIOSH-Publication; NIOSH-Grant; Noise-induced-hearing-loss; Laboratory-animals; Ears; Cell-function; Cell-morphology; Cellular-structures
Callier Ctr/communic Disorders Callier Center 1966 Inwood Road Dallas, Tex 75235
University of Texas Dallas, Richardson, Texas