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Properties of the endotoxins produced by various gram-negative bacteria present in occupational environments.
Dutkiewicz-J; Skorska-C; Sitkowska-J; Ochalska-B; Kaczmarski-F
Cotton dust: proceedings of the Twelfth Cotton Dust Research Conference, beltwide cotton research conferences, January 6-7, 1988, New Orleans, Louisiana. Wakelyn PJ, Jacobs RR, Rylander R, Burrell R, Peterson Y, eds. Memphis, TN: The National Cotton Council of America, 1988 Jan; :187-189
A comparison was made between endotoxins derived from different gram negative bacteria occurring commonly in various working environments, using basic tests for biological potency and ultrastructural examination of the endotoxin preparations. Species selected for this study (and their sources) included Acinetobacter- calcoaceticus (poultry hatcheries, animal farms), Alcaligenes- faecalis (animal farms, herb processing plants), Erwinia-herbicola (grain stores and mills, cotton mills), and Enterobacter-sp (sawmills). The endotoxins produced by two enterobacterial species, Erwina-herbicola and Enterobacter-sp, were generally more potent than those produced by the two nonenterobacterial species. The differences between the endotoxic potency of the lipopolysaccharides produced by different species were not marked very clearly and usually did not exceed one order of magnitude. The typical shape of the endotoxin macromolecule produced by all the studied bacterial species was a collapsed disc measuring on average 35 to 80 nanometers. The authors suggest that such structural formations occur naturally by convolution of the outer membrane of live bacteria which are then shed.
Textiles-industry; Cotton-industry; Airborne-dusts; Plant-dusts; Bacterial-dusts; Byssinosis; Toxins; Animal-husbandry; Poultry-industry; Grain-dusts; Lumber-industry;
Wakelyn-PJ; Jacobs-RR; Rylander-R; Burrell-R; Peterson-Y
Cotton dust: proceedings of the Twelfth Cotton Dust Research Conference, beltwide cotton research conferences, January 6-7, 1988, New Orleans, Louisiana
Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division